Level of cognitive impairment predicts mortality in high-risk community samples: the memory and medical care study.
Level of cognitive impairment predicts mortality in high-risk community samples: the memory and medical care study.
复制标题
认知障碍水平可预测高风险社区样本的死亡率：记忆和医疗保健研究。
DOI：
10.1176/jnp.2006.18.4.543
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发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Rabins,PeterV
中科院分区：
文献类型：
--
作者：
Lee,HochangB;Kasper,JudyD;Shore,AndrewD;Yokley,JessicaL;Black,BettyS;Rabins,PeterV
METHODThe protocol for the MMCS was approved by the Committee on Human Research, the Institutional Review Board for the Johns Hopkins Bloomberg School of Public Health. The MMCS identified subjects from three previously established, community-based study samples conducted in Maryland. 7–10 Among the 1,802 subjects from these studies, 724 persons had Mini-Mental State Examination (MMSE) scores less than 24, or a decline of four or more points over two administrations, and were living in the community at the start of the MMCS. Each of the 512 subjects (71%) who consented to enrollment in the MMCS identified an individual who helped them most often with any daily activities and was most knowledgeable about the subject’s health status. These individuals also were asked to participate in the study and are referred to as the subject’s knowledgeable informant. Overall, knowledgeable informants were spouses (18.3%), adult children (45.0%), siblings (6.4%), other relatives (18.1%) or nonrelatives (12.3%) and lived in the same geographic area as the subject. Knowledgeable informants completed a baseline interview and three subsequent annual follow-up interviews, which consisted of the collection of demographics, general health information, and health service utilization information on the subject. In addition, the knowledgeable informant rated the subject’s behavioral and psychiatric symptoms based on the depression subscale of the Neuropsychiatric Inventory (NPI), 11 and the agitation and psychosis subscales of Behavior Symptom Rating Scale (BSRS). 12 Medicare records for each subject were available to corroborate data gathered from the knowledgeable informant. In case of discrepancy between the Medicare records and the knowledgeable informant’s report, the Medicare records were preferentially used.
