Seasonal influence on the admittance of pre‐eclampsia patients in Tygerberg Hospital
Seasonal influence on the admittance of pre‐eclampsia patients in Tygerberg Hospital
复制标题
季节对泰格伯格医院先兆子痫患者入院的影响
DOI：
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发表时间：
2008
影响因子：
4.3
通讯作者：
D. Steyn
中科院分区：
文献类型：
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作者：
A. Immink;S. Scherjon;R. Wolterbeek;D. Steyn
背景以往的研究表明，先兆子痫的发生是季节性分布的。这项回顾性研究旨在确定南非Tygerberg医院的入院人数和先兆子痫妇女的患病率是否存在季节性变化。方法.从2002年至2003年每个季节和月份的医院记录中获得诊断为先兆子痫、子痫或溶血性肝酶升高低血小板（HELLP）综合征（统称为先兆子痫）的女性人数。相关性用比值比（OR）进行分析。此外，还将这些数据与这一时期每天记录的开普敦气温以及每个月的总降雨量进行了比较。对先兆子痫的概率与温度和降雨量进行双变量逻辑回归。结果先兆子痫发生在所有入院的11.5%（1，329/11，585）。患病率在冬季最高（所有入院的先兆子痫患者中有13.6%）。冬季入院的女性发生先兆子痫的风险高于夏季入院的女性（OR =1.69，95% CI：1.07-1.53）。6月发生先兆子痫的风险高于2月（南非夏季，参考月）（OR =2.81，95% CI：2.06-3.83）。先兆子痫入院人数与每日最低温度之间存在显著相关性（r =-0.620，p = 0.032）。结论.先兆子痫在南非泰格伯格医院的冬季更常见。这些发现对未来与先兆子痫病因学相关的研究以及临床护理具有影响。
Background. Previous studies suggest that the occurrence of pre‐eclampsia is seasonally distributed. This retrospective study aims to determine whether there is a seasonal variation in the number of admissions and the prevalence of women with pre‐eclampsia in Tygerberg Hospital, South Africa. Methods. The number of women admitted with a diagnosis of pre‐eclampsia, eclampsia or haemolysis elevated liver enzymes low platelets (HELLP) syndrome (together called pre‐eclampsia) was obtained from hospital records from 2002 to 2003 for each season and month. Associations were analysed with Odds Ratios (OR). Furthermore, these data was compared with the Cape Town temperatures recorded on each day over the period, as well as the total rainfall for each month. Bivariate logistic regression of the probability of pre‐eclampsia on temperature and rainfall was performed. Results. Pre‐eclampsia occurred in 11.5% of all admissions (1,329/11,585). The prevalence was highest in winter (13.6% pre‐eclampsia patients from all admissions). Women admitted in winter had a higher risk of developing pre‐eclampsia compared to those admitted in summer (OR =1.69, 95% CI: 1.07–1.53). The risk of developing pre‐eclampsia in June was higher than in February (summer in South Africa, reference month) (OR =2.81, 95% CI: 2.06–3.83). There was a significant correlation between the number of admissions with pre‐eclampsia and the minimum daily temperature (r = −0.620, p = 0.032). Conclusions. Pre‐eclampsia occurs more frequently in winter at Tygerberg Hospital, South Africa. The findings have implications for future research related to the aetiology of pre‐eclampsia as well as for clinical care.