ResearchArticle Canonical Decomposition of Ictal Scalp EEG and Accurate Source Localisation: Principles and Simulation Study
ResearchArticle Canonical Decomposition of Ictal Scalp EEG and Accurate Source Localisation: Principles and Simulation Study
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研究文章发作期头皮脑电图的规范分解和准确的源定位：原理和模拟研究
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发表时间：
2007
期刊：
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通讯作者：
W. Paesschen
中科院分区：
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作者：
M. Vos;L. D. Lathauwer;B. Vanrumste;S. Huffel;W. Paesschen
信件应发送至Maarten De Vos，maarten.devos@esat.kuleuven. be接收日期：2007年2月16日;修订日期：2007年6月13日;接受日期：2007年10月2日Andrzej Cicelski建议：长期脑电图（EEG）记录在难治性部分性癫痫的术前评估中非常重要，可用于划定发作区。在本文中，我们介绍了一个新的概念，一个自动，快速，客观定位的发作发作区在发作脑电图记录。发作期脑电信号的正则分解是将脑电信号分解为原子。一个或多个原子与癫痫发作活动有关。在这项研究中，我们进行了模拟研究，以估计偶极子定位误差。即使在低信噪比下，发作偶极子定位也非常准确，不受发作活动频率或频率变化的影响，并且受发作区位置的波形和深度的影响最小。使用21个电极时，癫痫偶极子定位误差约为10.0mm，使用148个通道时，在0.5-1.0mm范围内改善了10倍以上。总之，我们对发作头皮EEG的典型分解的模拟研究可以对发作区进行鲁棒且准确的定位。版权所有© 2007 Maarten De Vos等人。这是一篇开放获取文章，根据知识共享署名许可证分发，该许可证允许无限制地使用、分发和复制在任何媒体上，前提是正确引用了原创作品。
Correspondence should be addressed to Maarten De Vos, maarten.devos@esat.kuleuven.beReceived 16 February 2007; Revised 13 June 2007; Accepted 2 October 2007Recommended by Andrzej CichockiLong-term electroencephalographic (EEG) recordings are important in the presurgical evaluation of refractory partial epilepsy forthe delineation of the ictal onset zones. In this paper, we introduce a new concept for an automatic, fast, and objective localisationof the ictal onset zone in ictal EEG recordings. Canonical decomposition of ictal EEG decomposes the EEG in atoms. One or moreatoms are related to the seizure activity. A single dipole was then fitted to model the potential distribution of each epileptic atom.In this study, we performed a simulation study in order to estimate the dipole localisation error. Ictal dipole localisation was veryaccurate, even at low signal-to-noise ratios, was not affected by seizure activity frequency or frequency changes, and was minimallyaffected by the waveform and depth of the ictal onset zone location. Ictal dipole localisation error using 21 electrodes was around10.0mm and improved more than tenfold in the range of 0.5–1.0mm using 148 channels. In conclusion, our simulation study ofcanonical decomposition of ictal scalp EEG allowed a robust and accurate localisation of the ictal onset zone.Copyright © 2007 Maarten De Vos et al. This is an open access article distributed under the Creative Commons AttributionLicense, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properlycited.