MICROBIAL-FLORA IN EYES OF CURRENT AND FORMER CONTACT-LENS WEARERS
MICROBIAL-FLORA IN EYES OF CURRENT AND FORMER CONTACT-LENS WEARERS
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DOI：
10.1128/jcm.30.5.1156-1161.1992
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发表时间：
1992-05-01
影响因子：
9.4
通讯作者：
EFRON, N
中科院分区：
文献类型：
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作者：
FLEISZIG, SMJ;EFRON, N
对84例连续配戴角膜接触透镜患者的右眼结膜囊进行了微生物植物群的检测，并与无菌取出后透镜两面的培养物及存放盒的植物群进行了比较。 从每个个体的接触透镜和结膜培养物中获得了相似的结果;然而，储存盒分离株与透镜或结膜植物群之间不存在相关性，这表明在简单的透镜配戴中，眼睛在根除通过处理引入的微生物方面非常有效。 每日配戴角膜接触镜期间的结膜植物群与匹配对照组非透镜配戴者的结膜植物群相似。 然而，被认为是正常眼部植物群的一部分的细菌从以前的接触透镜配戴者中分离出来的频率显著更高。 数据还表明，对于当前和既往接触透镜配戴者，使用非过氧化物化学透镜消毒与比使用其他形式消毒更高比例的病原微生物阳性培养物相关。 潜在病原体的分离在长期配戴厚角膜接触镜的老年受试者中特别常见。 结膜植物群的这些变化可能导致与接触透镜配戴相关的眼部感染风险增加。
Microbial flora from the right eye conjunctival sac of 84 consecutively presenting contact lens patients were compared with cultures from both surfaces of their lens after aseptic removal and with the flora of their storage cases. Similar results were obtained from contact lens and conjunctival cultures of each individual; however, there was no correlation between storage case isolates and lens or conjunctival flora, suggesting that in uncomplicated lens wear, the eye is highly efficient in eradicating microorganisms introduced via handling. Conjunctival flora during daily contact lens wear was similar to the conjunctival flora of a matched control group of non-lens wearers. However, bacteria that are considered to be part of the normal ocular flora were isolated significantly more often from former contact lens wearers. The data also indicated that the use of nonperoxide chemical lens disinfection was associated with a higher proportion of positive cultures for pathogenic microorganisms than the use of other forms of disinfection, for both current and former contact lens wearers. The isolation of potential pathogens was particularly common among elderly subjects using thick contact lenses for extended wear. These changes to conjunctival flora may contribute to the increased risk of ocular infection associated with contact lens wear.