RNA polymerase III transcriptional units are interspersed among human non-alpha-globin genes.
RNA polymerase III transcriptional units are interspersed among human non-alpha-globin genes.
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RNA 聚合酶 III 转录单位散布在人类非 α 珠蛋白基因中。
DOI：
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发表时间：
1979
影响因子：
11.1
通讯作者：
S. Weissman
中科院分区：
文献类型：
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作者：
C. Duncan;P. Biro;P. Choudary;James T. Elder;R. R. Wang;B. Forget;J. de Riel;S. Weissman
含有珠蛋白基因的克隆的人类DNA片段在体外转录，形成离散的RNA物种。一个转录单位位于G-γ-珠蛋白基因上游约1500个碱基对。该转录本与位于β-珠蛋白基因上游约1000个碱基对的聚合酶III模板部分同源，与位于β-珠蛋白基因下游短距离的DNA部分同源。
Cloned human DNA fragments containing globin genes are transcribed in vitro to form discrete RNA species. One transcription unit is located approximately 1500 base pairs upstream from the G-gamma-globin gene. This transcript is partially homologous to a polymerase III template located approximately 1000 base pairs upstream from the delta-globin gene and to DNA located a short distance downstream from the beta-globin gene.