Copper‐catalyzed Asymmetric Ring‐opening of Cyclic Diaryliodonium with Benzyl and Aliphatic Amines
Copper‐catalyzed Asymmetric Ring‐opening of Cyclic Diaryliodonium with Benzyl and Aliphatic Amines
复制标题
铜催化环状二芳基碘与苄基和脂肪胺的不对称开环
DOI：
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
Zhenhua Gu
中科院分区：
文献类型：
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作者：
Shibo Xu;Kun Zhao;Zhenhua Gu
开发了一种环二芳基碘鎓盐与苄基胺或脂肪胺之间的铜催化不对称开环反应。通过将胺与路易斯酸混合或缓慢加入胺来实现低浓度的胺时，该反应能以高对映选择性得到产物。
A Cu‐catalyzed asymmetric ring‐opening reaction between cyclic diaryliodonium and benzylic or aliphatic amines has been developed. At low concentration of the amines, realized by either mixing the amines with Lewis acid or slow addition of the amines, the reaction afforded the products in high enantioselectivity.