Bilateral Leser-Trélat Sign Mirroring Lung Adenocarcinoma with Early Metastases to the Contralateral Lung
Bilateral Leser-Trélat Sign Mirroring Lung Adenocarcinoma with Early Metastases to the Contralateral Lung
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DOI：
10.1097/smj.0b013e31818f604d
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发表时间：
2009-02
影响因子：
1.1
通讯作者：
C. Dasanu;D. Alexandrescu
中科院分区：
文献类型：
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作者：
C. Dasanu;D. Alexandrescu
我们报告一例肺腺癌累及的身体部位与Leser-Trélat皮肤副肿瘤征重叠的病例。在我们的患者中，Leser-Trélat征由爆炸性多发性脂溢性角化病合并黑棘皮病组成，代表肺癌累及两个上叶的显著几何皮肤投影。我们的病例提示Leser-Trélat的副肿瘤征与肿瘤本身之间存在独特的相互关系。认识到这一现象可能有助于早期诊断和及时手术治疗隐匿性癌症。
We present a case featuring a unique overlap between the body areas involved by lung adenocarcinoma and the cutaneous paraneoplastic sign of Leser-Trélat. In our patient, the Leser-Trélat sign consisted of explosive multiple seborrheic keratoses in combination with acanthosis nigricans, representing a remarkable geometric skin projection of lung cancer which involved both the upper lobes. Our case suggests a unique interrelation between the paraneoplastic sign of Leser-Trélat and the tumor itself. The recognition of this phenomenon may contribute to an early diagnosis and prompt surgical treatment of occult cancers.