Diet quality and risk of neural tube defects
Diet quality and risk of neural tube defects
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DOI：
10.1016/s0306-9877(02)00402-4
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发表时间：
2003-03-01
影响因子：
4.7
通讯作者：
Schaffer, DM
中科院分区：
文献类型：
--
作者：
Carmichael, SL;Shaw, GM;Schaffer, DM
许多研究探讨了单一营养素（尤其是叶酸）对神经管缺陷 (NTD) 风险的影响。饮食模式或营养素组合的影响受到的关注要少得多。本研究使用基于人口的 NTD 病例对照研究（n = 454 例和 462 例对照）的食物频率数据，探讨了饮食质量与 NTD 风险之间的关联。饮食质量评分基于铁、维生素 136 和维生素 A、钙、叶酸的摄入量低值（第 90 个百分位），以及来自脂肪和甜食的千卡百分比（范围 = 0-14）。得分较低的女性（即
Many studies have examined the impact of single nutrients on neural tube defect (NTD) risk, particularly folate. The impact of dietary patterns or nutrients in combination has received much less attention. This study examines the association of diet quality with NTD risk, using food frequency data from a population-based case-control study of NTDs (n = 454 cases and 462 controls). The diet quality score was based on low (90th percentile) values for intakes of iron, vitamins 136 and A, calcium, folate, and percentage of kilocalories from fat and from sweets (range = 0-14). Women with a low score (i.e.,