RefPlantNLR: a comprehensive collection of experimentally validated plant NLRs
RefPlantNLR: a comprehensive collection of experimentally validated plant NLRs
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DOI：
10.1101/2020.07.08.193961
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发表时间：
2020-07
期刊：
影响因子：
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通讯作者：
Jiorgos Kourelis;S. Kamoun
中科院分区：
文献类型：
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作者：
Jiorgos Kourelis;S. Kamoun
参考数据集在计算生物学中至关重要。它们有助于定义典型的生物学特征，对基准研究至关重要。在这里，我们描述了一个经过实验验证的植物NLR免疫受体的综合参考数据集。RefPlantNLR收录了开花植物11目31属415个nlr。我们使用RefPlantNLR来确定功能性验证的植物nlr的典型特征。该参考数据集将有助于对NLR标注工具进行基准测试，指导跨广泛植物多样性的NLR比较分析，并确定研究不足的分类群。我们希望RefPlantNLR资源将有助于推动该领域超越对NLR结构和功能的统一看法。
Reference datasets are critical in computational biology. They help define canonical biological features and are essential for benchmarking studies. Here, we describe a comprehensive reference dataset of experimentally validated plant NLR immune receptors. RefPlantNLR consists of 415 NLRs from 31 genera belonging to 11 orders of flowering plants. We used RefPlantNLR to determine the canonical features of functionally validated plant NLRs. This reference dataset should prove useful for benchmarking NLR annotation tools, guiding comparative analyses of NLRs across the wide spectrum of plant diversity and identifying under-studied taxa. We hope that the RefPlantNLR resource will contribute to moving the field beyond a uniform view of NLR structure and function.