SENSORIMOTOR ENCODING BY SYNCHRONOUS NEURAL ENSEMBLE ACTIVITY AT MULTIPLE LEVELS OF THE SOMATOSENSORY SYSTEM
SENSORIMOTOR ENCODING BY SYNCHRONOUS NEURAL ENSEMBLE ACTIVITY AT MULTIPLE LEVELS OF THE SOMATOSENSORY SYSTEM
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DOI：
10.1126/science.7761855
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发表时间：
1995-06-02
期刊：
影响因子：
56.9
通讯作者：
CHAPIN, JK
中科院分区：
文献类型：
--
作者：
NICOLELIS, MAL;BACCALA, LA;CHAPIN, JK
在行为过程中的感觉运动信息的神经集成处理进行了研究，同时记录多达48个单一的神经元在多个继电器的大鼠三叉神经体感系统。皮层、丘脑和脑干神经元表现出广泛的7- 12赫兹同步振荡，这种振荡开始于注意力不动期间，并可靠地预测了即将发生的有节奏的胡须抽搐。每一个振荡周期开始于皮层神经活动的行波，然后传播到丘脑。就在有节奏的胡须抽搐发作之前，振荡传播到三叉神经脊束脑干复合体。此后，在所有级别的振荡是同步的晶须伸长。体现这些节奏的神经结构也表现出分布式的时空模式的神经元合奏活动在触觉刺激，因此，在这个系统中的多级同步活动不仅可以编码的感觉信息，但也开始和触觉探索运动的时域。
Neural ensemble processing of sensorimotor information during behavior was investigated by simultaneously recording up to 48 single neurons at multiple relays of the rat trigeminal somatosensory system. Cortical, thalamic, and brainstem neurons exhibited widespread 7- to 12-hertz synchronous oscillations, which began during attentive immobility and reliably predicted the imminent onset of rhythmic whisker twitching. Each oscillatory cycle began as a traveling wave of neural activity in the cortex that then spread to the thalamus. Just before the onset of rhythmic whisker twitching, the oscillations spread to the spinal trigeminal brainstem complex. Thereafter, the oscillations at all levels were synchronous with whisker protraction. Neural structures manifesting these rhythms also exhibited distributed spatiotemporal patterns of neuronal ensemble activity in response to tactile stimulation, thus, multilevel synchronous activity in this system may encode not only sensory information but also the onset and temporal domain of tactile exploratory movements.