Outbreak of paralysis in Morocco due to ortho-cresyl phosphate poisoning.
Outbreak of paralysis in Morocco due to ortho-cresyl phosphate poisoning.
复制标题
DOI：
10.1016/s0140-6736(59)91486-2
复制
发表时间：
1959-12
期刊：
影响因子：
168.9
通讯作者：
H. V. Smith;J. Spalding
中科院分区：
文献类型：
--
作者：
H. V. Smith;J. Spalding
1959 年 9 月 25 日，我们以“世界卫生组织临时顾问的身份前往摩洛哥，为摩洛哥卫生当局调查一场不明来源的瘫痪疾病的爆发提供建议”。正在与摩洛哥的同事一起准备对疫情的全面报道，但鉴于最近的报纸报道，我们个人经历的简短报道可能会引起兴趣。此外，磷酸甲苯酯（通常包括磷酸邻甲苯酯（OCP））具有许多工业用途，因为它们非常热稳定并且也是重要的增塑剂。尽管OCP在工业用户中因其毒性而臭名昭著，并且在使用时必须严格采取预防措施，但我们不能忘记中毒的可能性。当我们到达摩洛哥时，摩洛哥卫生部门已经收集了大量流行病学和统计信息，并在我们总部所在的摩洛哥行政首都拉巴特向我们提供了这些信息。
We went to Morocco on September 25, 1959, as “temporary advisers to the World Health Organization in order to advise the Moroccan health authorities in investigating an outbreak of a paralyzing disease of unknown origin.” A full account of the outbreak is in preparation in association with colleagues in Morocco, but in view of recent newspaper reports a short account of our personal experience may be of interest. Moreover, cresyl phosphates, which commonly include ortho-cresyl phosphate (OCP), have many industrial uses, because they are very heat-stable and are also important plasticizers. Although OCP is notorious among industrial users for its toxicity, and it is used only with strict precautions, the possibility of poisoning must not be forgotten. When we reached Morocco, a large amount of epidemiological and statistical information had already been collected by the Moroccan health authorities, and was made available to us in Rabat, the administrative capital of Morocco, where we had our headquarters.