Wash-free 3D imaging and detection of glioma with a novel neuropotential targeted AIE probe
Wash-free 3D imaging and detection of glioma with a novel neuropotential targeted AIE probe
复制标题
DOI：
10.1039/d0cc07289c
复制
发表时间：
2021-01-18
影响因子：
4.9
通讯作者：
Zeng, Wenbin
中科院分区：
文献类型：
--
作者：
Wu, Junyong;Bi, Anyao;Zeng, Wenbin
在此，我们开发了一种基于四芳基咪唑的新型AIE探针TPIG-NP，用于选择性成像和定量检测胶质瘤。由于胶质瘤细胞带明显的负电荷，带相反电荷的TPIG-NP可以实现对胶质瘤细胞和3D多细胞球体的免清洗成像。
We herein developed a novel tetraarylimidazole-based AIE probe TPIG-NP to selectively image and quantitatively detect glioma. Due to the distinct negatively charged glioma cells, TPIG-NP with an opposite charge could achieve wash-free imaging of glioma cells and 3D multicellular spheroids.