Zoonotic Mycobacterium bovis-induced tuberculosis in humans.
Zoonotic Mycobacterium bovis-induced tuberculosis in humans.
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DOI：
10.3201/eid1906.120543
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发表时间：
2013-06
影响因子：
11.8
通讯作者：
Zinsstag J
中科院分区：
文献类型：
--
作者：
Müller B;Dürr S;Alonso S;Hattendorf J;Laisse CJ;Parsons SD;van Helden PD;Zinsstag J
我们旨在通过对过去20年的相关科学文献进行多语言、系统的回顾和分析，估计由牛分枝杆菌或卡普拉分枝杆菌感染引起的人类人畜共患结核病（TB）的全球发生率。虽然没有来自世界许多地方的信息，但来自61个国家的数据表明，全球发病率很低。在本研究包括的非洲以外地区，人畜共患结核病的总体中位数比例≤1.4%，与结核病总发病率≤71/10万人/年有关，表明发病率较低。对于纳入研究的非洲国家，我们将观察到的人畜共患结核病例中位数比例（2.8%）与大陆平均结核总发病率（264/10万人/年）相乘，得出粗略估计为7例人畜共患结核病例/10万人/年。尽管发病率普遍较低，但现有数据表明，这种疾病对某些人群和环境造成了严重后果。
We aimed to estimate the global occurrence of zoonotic tuberculosis (TB) caused by Mycobacterium bovis or M. caprae infections in humans by performing a multilingual, systematic review and analysis of relevant scientific literature of the last 2 decades. Although information from many parts of the world was not available, data from 61 countries suggested a low global disease incidence. In regions outside Africa included in this study, overall median proportions of zoonotic TB of ≤1.4% in connection with overall TB incidence rates ≤71/100,000 population/year suggested low incidence rates. For countries of Africa included in the study, we multiplied the observed median proportion of zoonotic TB cases of 2.8% with the continental average overall TB incidence rate of 264/100,000 population/year, which resulted in a crude estimate of 7 zoonotic TB cases/100,000 population/year. These generally low incidence rates notwithstanding, available data indicated substantial consequences of this disease for some population groups and settings.