Amazing IL-9: revealing a new function for an "old" cytokine.
Amazing IL-9: revealing a new function for an "old" cytokine.
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DOI：
10.1172/jci65929
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发表时间：
2012-11
期刊：
影响因子：
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通讯作者：
E. Schmitt;T. Bopp
中科院分区：
文献类型：
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作者：
E. Schmitt;T. Bopp
黑色素瘤-最具侵袭性的皮肤癌形式-的发病率正在急剧增加，而创新治疗策略的开发仍然具有挑战性，特别是由于缺乏对黑色素瘤进展以及抗肿瘤免疫的分子机制的了解。在本期JCI中，Yong Lu及其同事报告了Th 9细胞在抗肿瘤免疫中的核心作用。
The incidence of melanoma - the most aggressive form of skin cancer - is dramatically increasing, while the development of innovative therapeutic strategies continues to be challenging, especially due to a lack of knowledge about the molecular mechanisms underlying melanoma progression as well as antitumor immunity. In this issue of the JCI, Yong Lu and colleagues report a central role for Th9 cells in antitumor immunity.