The advantages and limitations of permanent or reversible deactivation techniques in the assessment of neural function

The advantages and limitations of permanent or reversible deactivation techniques in the assessment of neural function
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DOI:
10.1016/s0165-0270(98)00160-5
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发表时间:
1999-01-01
影响因子:
3
通讯作者:
Lomber, SG
Lomber, SG
中科院分区:
医学4区
文献类型:
--
作者:
Lomber, SG

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本综述考虑了不同形式的可逆失活以及它们彼此之间以及与更传统的永久失活方法的区别。讨论了化学和冷却可逆灭活的不同方法以及每种方法的局限性。最后,考虑了以下方面的未来方向:探索实验动物的大脑功能定位,以及这项工作如何与目前用于人类的新兴非侵入性成像技术相关。 (C) 1999 Elsevier Science B.V. 保留所有权利。
This review considers the different forms of reversible deactivation and how they differ from each other and from more conventional permanent deactivation methods. The different methods of chemical and cooling reversible inactivation and the limitations of each are discussed. Finally, future directions in the: quest to localize brain function in the experimental animal are considered and how this work relates to emerging non-invasive imaging techniques presently being used with humans. (C) 1999 Elsevier Science B.V. All rights reserved.