MORTALITY FROM PULMONARY-EMBOLISM IN THE UNITED-STATES - 1962 TO 1984
MORTALITY FROM PULMONARY-EMBOLISM IN THE UNITED-STATES - 1962 TO 1984
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DOI：
10.1378/chest.98.5.1067
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发表时间：
1990-11-01
期刊：
影响因子：
9.6
通讯作者：
MARSH, G
中科院分区：
文献类型：
--
作者：
LILIENFELD, DE;CHAN, E;MARSH, G
为了检验在预防和治疗PE方面的进展的效果，我们回顾了1962-1984年间美国的PE死亡率。在1962年至1974年期间，白人和非白人男性和女性的年龄调整后的PE死亡率增加了67%至100%。从1975年到1984年，这些利率下降了20%到28%。非白人PE死亡率高于白人PE死亡率；男性PE死亡风险高于女性。特定年龄组(40岁以上)的PE死亡率模式紧随年龄调整死亡率的模式，1962至1974年间所有群体的死亡率均有所上升，1975至1984年期间有所下降。这些模式可能反映了对病例查明的改进和对疾病的更好预防。这一比率的大小表明，预防性抗凝的适应症清单应该重新审查，以确定是否可能扩大。
To examine the effect of advances in the prevention of and therapy for PE, we reviewed mortality for PE in the United States from 1962 to 1984. Age-adjusted PE mortality increased by 67 to 100 percent between 1962 and 1974 for white and non-white men and women. From 1975 and 1984, these rates declined by 20 to 28 percent. Non-white PE mortality was greater than white PE mortality; men had a greater risk of PE death than women. Age-specific patterns (more than 40 years of age) of PE mortality followed those of the age-adjusted death rates, with increases noted in all groups between 1962 and 1974 and declines during the 1975-1984 period. These patterns might reflect improved ascertainment of cases and better prevention of disease. The magnitude of the rates suggests that the list of indications for prophylactic anticoagulation should be reexamined for possible expansion.