Magnetic resonance studies of brain lesions in patients with Kawasaki disease
Magnetic resonance studies of brain lesions in patients with Kawasaki disease
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DOI：
10.1016/j.braindev.2005.04.003
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发表时间：
2006-01-01
影响因子：
1.7
通讯作者：
Hara, T
中科院分区：
文献类型：
--
作者：
Muneuchi, J;Kusuhara, K;Hara, T
我们通过磁共振成像（MRI）和磁共振血管造影（MRA）评估川崎病（KD）并发冠状动脉病变（CAL）患者的脑部病变。在1996年4月至2004年9月在九州大学医院接受冠状动脉造影以评估由于KD引起的CAL的47名患者中，24名患者在KD发病后0.1-21.2年通过脑MRI和MRA进行了前瞻性评估。虽然大多数患者有易怒或嗜睡，但在急性期，除1例颈部僵硬外，无1例出现明显的神经系统症状或体征。在24例患者中，1例无明显神经系统症状，脑MRI和MRA分别显示右侧小脑梗死和右侧小脑后下动脉闭塞。这些结果表明，在24例伴CAL的KD患者中，有1例存在脑血管病变，提示在伴或不伴神经系统症状的KD重症病例中，需要考虑脑病变的可能性。(c)2005 Elsevier B. V.保留所有权利。
We evaluated brain lesions in patients with coronary arterial lesions (CAL) as a complication of Kawasaki disease (KD) by magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA). Among 47 patients who underwent coronary angiography for the evaluation of CAL due to KD at Kyushu University Hospital from April 1996 to September 2004, 24 patients were evaluated prospectively by brain MRI and MRA 0.1-21.2 years after the onset of KD. Although most patients had irritability or lethargy, none of them had significant neurological symptoms or signs during the acute phase, except one who showed neck stiffness. In one patient with no apparent neurological symptoms out of the 24 patients, brain MRI and MRA revealed right cerebellar infarction and obliteration of the right posterior inferior cerebellar artery, respectively. These results revealed the presence of cerebrovascular lesion in one of the 24 KD patients with CAL and suggested the need to consider the possibility of brain lesions in severe cases of KD with or without neurological symptoms. (c) 2005 Elsevier B.V. All rights reserved.