Pharmaceuticals, personal care products and endocrine-disrupting chemicals in U.S. surface and finished drinking waters: A proposed ranking system
Pharmaceuticals, personal care products and endocrine-disrupting chemicals in U.S. surface and finished drinking waters: A proposed ranking system
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DOI：
10.1016/j.scitotenv.2010.08.048
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发表时间：
2010-11-01
影响因子：
9.8
通讯作者：
Xagoraraki, Irene
中科院分区：
文献类型：
--
作者：
Kumar, Arun;Xagoraraki, Irene
据作者所知，本研究首次开发了一个综合排名系统，用于优先监测药品和个人护理产品以及内分泌干扰化学品（统称为EOC）。下文中考虑总共100个EOC）（下文中称为“EOCRank”）。EOCRank系统使用总共4个标准（1）发生率来开发。(2)饮用水处理厂的处理，（3）生态影响和（4）健康影响，并使用流行率、检测频率、去除、生物累积、生态毒性（对鱼类、水蚤和藻类水生指示物种）、怀孕影响和健康影响7个属性进行表征。使用致癌性、致突变性、生育力损害、中枢神经系统作用、内分泌效应、免疫毒性、EOCs的等级得分计算为多个标准的重要性权重和效用函数的乘积之和，并排列以突出需要立即关注的EOCs。S成品饮用水和溪流水/水源水，并观察到彼此不同，表明水的类型对EOC的排名的影响。使用特定标准开发的优先EOC的排名列表被观察到与使用多个标准开发的不同。健康影响和治疗标准被认为是影响总体数据差距排名分数的重要标准，需要进一步收集数据。（不同成分的发生率信息和重要性权重）已开发的EOCRank系统数据库可在http：//www.orgmsuedu/-xagorara/researchhtml上查阅）（C）2010爱思唯尔B V版权所有
This study developed a comprehensive ranking system, for the first time as per authors knowledge, for prioritizing the monitoring of pharmaceuticals and personal care products and endocrine-disrupting chemicals (together termed as EOCs. hereafter, a total of 100 EOCs considered) in US stream water/source water and finished drinking water (termed as "EOCRank," hereafter) The EOCRank system was developed using a total of 4 criteria (1) occurrence. (2) treatment in drinking water treatment plants, (3) ecological effects, and (4) health effects and characterized using 7 attributes prevalence, frequency of detection, removal, bioaccumulation, ecotoxicity (for fish, daphnid, and algae aquatic indicator species), pregnancy effects, and health effects. The health effects attribute was characterized using 7 sub-attributes carcinogenicity, mutagenicity, impairment of fertility, central nervous system acting, endocrine effects, immunotoxicity, and developmental effects Rank scores of EOCs were calculated as summations of multiplications of importance weights and utility functions of multiple criteria and were arranged to highlight EOCs needing immediate attention Two different ranking lists of EOCs were developed for U S finished drinking water and stream water/source water and observed to differ with each other, indicating the effect of water type on ranking of EOCs A ranking list of priority EOCs, developed using a particular criterion, was observed to differ with that, developed using multiple criteria. Health effects and treatment criteria were observed to be important criteria influencing overall data gap rank scores and need further data collection The generalized nature of the system could he customized for specific geographical locations (occurrence information and importance weights of different components) The developed database of the EOCRank system is available on http //www egr msu edu/-xagorara/research html) (C) 2010 Elsevier B V All rights reserved