High-resolution imaging without iteration: A fast and robust method for breast ultrasound tomography
High-resolution imaging without iteration: A fast and robust method for breast ultrasound tomography
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DOI：
10.1121/1.3613936
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发表时间：
2011-09-01
影响因子：
2.4
通讯作者：
Simonetti, F.
中科院分区：
文献类型：
--
作者：
Huthwaite, P.;Simonetti, F.
相对于金标准的乳房x光检查，乳房超声断层扫描有可能提高乳腺癌筛查和诊断的成本、安全性和可靠性。实现这一潜力的关键是成像算法的发展，以揭示乳房的复杂解剖结构及其力学特性。最常用的解决方案是飞行时间层析成像，但由于存在衍射效应，这种方法的分辨率很低。迭代全波反演方法提供了一种获得更高分辨率的解，但这些方法速度慢，不能保证收敛到正确的解。本文介绍的是HARBUT，一种鲁棒乳腺超声断层扫描的混合算法，它利用了光时和衍射断层扫描的互补优势，从而产生了一种直接、快速、鲁棒和准确的高分辨率方法来重建通过乳房的声速。该算法被证明可以用复杂的三维模拟的真实数据产生精确的重建，小到4毫米的质量清晰可见。(C) 2011美国声学学会。(DOI: 10.1121/1.3613936)
Breast ultrasound tomography has the potential to improve the cost, safety, and reliability of breast cancer screening and diagnosis over the gold-standard of mammography. Vital to achieving this potential is the development of imaging algorithms to unravel the complex anatomy of the breast and its mechanical properties. The solution most commonly relied upon is time-of-flight tomography, but this exhibits low resolution due to the presence of diffraction effects. Iterative full-wave inversion methods present one solution to achieve higher resolution, but these are slow and are not guaranteed to converge to the correct solution. Presented here is HARBUT, the hybrid algorithm for robust breast ultrasound tomography, which utilizes the complementary strengths of time-off-light and diffraction tomography resulting in a direct, fast, robust and accurate high resolution method of reconstructing the sound speed through the breast. The algorithm is shown to produce accurate reconstructions with realistic data from a complex three-dimensional simulation, with masses as small as 4 mm being clearly visible. (C) 2011 Acoustical Society of America. [DOI: 10.1121/1.3613936]