Clinical Application of Biotechnically Cultured Autologous Chondrocytes as Novel Graft Material for Nasal Augmentation
Clinical Application of Biotechnically Cultured Autologous Chondrocytes as Novel Graft Material for Nasal Augmentation
复制标题
生物技术培养的自体软骨细胞作为新型隆鼻移植材料的临床应用
作者：
H. Yanaga;Mika Koga;K. Imai;K. Yanaga
一种新的隆鼻方法是将培养的自体软骨细胞移植到鼻部。利用生物技术，一块1平方厘米的软骨被培养成凝胶型软骨细胞块，然后通过注射将其移植到鼻背上通过手术创造的骨膜下皮肤口袋中。用胶带包裹隆鼻，保护1周。移植的软骨细胞在大约1个月后发育为成熟的软骨组织。该方法应用于8例隆鼻术，1例同期隆下术，1例额部凹陷畸形。经6~24个月的随访，结果令人满意。作者认为，这种方法至少可以部分取代硅胶隆鼻术。
A new method of nasal augmentation has been developed, in which cultured autologous chondrocytes are transplanted. Using biotechnology, a piece of the choncha cartilage 1 cm2 is cultured into a gel-type mass of chondrocytes, which then is transplanted by injection into a surgically created subperiosteal skin pocket on the nasal dorsum. The augmented nose is taped and protected for 1 week. The grafted chondrocytes develop into mature cartilaginous tissue after approximately 1 month. This method was used in eight cases of nasal augmentation, and one case of chin augmentation (performed simultaneously), and one case of depressed deformity on the forehead. The results obtained by this method to date have been satisfactory after a follow-up time of 6 to 24 months. The authors believe that this method may at least partially be able to replace silicone implantation for nasal augmentation.
影响因子：
3.6
作者：
G. V. Osch;Simone W. van der Veen;H. L. Verwoerd-Verhoef
通讯作者：
G. V. Osch;Simone W. van der Veen;H. L. Verwoerd-Verhoef