Selective association of cholesterol with long-chain phospholipids in liquid-ordered bilayers: Support for the existence of lipid rafts
Selective association of cholesterol with long-chain phospholipids in liquid-ordered bilayers: Support for the existence of lipid rafts
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DOI：
10.1021/ja038102n
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发表时间：
2003-10-29
影响因子：
15
通讯作者：
Regen, SL
中科院分区：
文献类型：
--
作者：
Sugahara, M;Uragami, M;Regen, SL
最近邻识别实验，这已经进行了流化和冷凝条件下，使用可交换的二聚体衍生自1，2-二肉豆蔻酰-sn-甘油-3-磷酸乙醇胺，1，2-二硬脂酰-sn-甘油-3-磷酸乙醇胺，和胆固醇，提供了强有力的证据，甾醇磷脂识别限于液体有序相。
Nearest-neighbor recognition experiments, which have been carried out under fluidizing and condensing conditions, using exchangeable dimers derived from 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine, and cholesterol, have provided strong evidence that sterol-phospholipid recognition is limited to the liquid-ordered phase.