Initiation of ectopic epithelial calcification in a calcifying odontogenic cyst.
Initiation of ectopic epithelial calcification in a calcifying odontogenic cyst.
复制标题
钙化性牙源性囊肿中异位上皮钙化的起始。
DOI：
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发表时间：
2007
影响因子：
3.3
通讯作者：
Masaru Nagayama
中科院分区：
文献类型：
--
作者：
K. Satomura;H. Nakanishi;Kenji Fujisawa;E. Hayashi;Masaru Nagayama
对一名 8 岁日本男孩右下颌区域出现的与牙瘤相关的钙化性牙源性囊肿 (COC) 进行超微结构观察。 COC 上皮层中鉴定出四种类型的细胞。基底细胞呈低柱状，含有一些细胞内细胞器。它们通过一些桥粒附着在邻近的细胞上，类似于正常牙釉质器官的内牙釉质上皮。星状网状细胞呈多边形，具有桥粒和许多细胞质突起。细胞质中可见一些细胞内细胞器和几束张力丝。用甲苯胺蓝染色的淡椭圆形细胞含有扩张的膜细胞器和许多相对均匀分布的张力丝。这些细胞通常分散在鬼细胞聚集点附近，部分细胞膜不连续。影细胞含有许多直径60-240 nm、排列在不同方向的张力丝。细胞质中没有发现完整的细胞内细胞器。它们通过一些桥粒附着在邻近的鬼细胞上，并且它们的细胞膜部分不连续。直径90-450 nm的各种囊泡散布在张力丝束之间。其中一些含有针状晶体，被认为是鬼细胞中的初始钙化位点。这些囊泡呈现出与基质囊泡的形态相似性，因此表明基质囊泡样结构与COC中鬼细胞钙化的起始密切相关。
Ultrastructural observation was performed on a calcifying odontogenic cyst (COC) associated with an odontoma and arising in the right mandibular region of an 8-year-old Japanese boy. Four types of cells were identified in the epithelial layer of the COC. The basal cells were low columnar in shape and contained some intracellular organelles. They were attached to the neighboring cells with a few desmosomes and resembled inner enamel epithelium of the normal enamel organ. The stellate reticulum-like cells, polygonal in shape, possessed desmosomes and many cytoplasmic projections. Some intracellular organelles and a few bundles of tonofilaments were observed in the cytoplasm. The light oval cells that were pale staining with toluidine blue contained dilated membranous organelles and many relatively evenly distributed tonofilaments. These cells were usually scattered in the vicinity of the focal accumulations of ghost cells, and the cell membrane was discontinuous in parts. The ghost cells contained many bundles of tonofilaments that were 60-240 nm in diameter and arranged in various directions. No intact intracellular organelles were noted in the cytoplasm. They were attached to the neighboring ghost cells with some desmosomes and their cell membrane was discontinuous in parts. A variety of vesicles, 90-450 nm in diameter, were scattered among the tonofilament bundles. Some of these contained needle-like crystals that were considered to be initial calcification sites in ghost cells. These vesicles presented morphological similarities to matrix vesicles, and it is therefore suggested that matrix vesicle-like structures are deeply involved with initiation of calcification of ghost cells in COC.
影响因子：
4.6
作者：
Anderson,HC
通讯作者：
Anderson,HC