Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan
Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan
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DOI：
10.3201/eid2609.201353
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发表时间：
2020-09-01
影响因子：
11.8
通讯作者：
Suzuki, Tadaki
中科院分区：
文献类型：
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作者：
Adachi, Takuya;Chong, Ja-Mun;Suzuki, Tadaki
日本一名冠状病毒病患者的尸检显示肺炎肺部病理，表现为弥漫性肺泡损伤。肺泡上皮细胞和巨噬细胞中检测到严重急性呼吸综合征冠状病毒2抗原。冠状病毒病本质上是一种下呼吸道疾病，其特征是肺泡上皮细胞的直接病毒损伤。
An autopsy of a patient in Japan with coronavirus disease indicated pneumonia lung pathology, manifested as diffuse alveolar damage. We detected severe acute respiratory syndrome coronavirus 2 antigen in alveolar epithelial cells and macrophages. Coronavirus disease is essentially a lower respiratory tract disease characterized by direct viral injury of alveolar epithelial cells.