The impact of obesity on health-related quality-of-life in the general adult US population
The impact of obesity on health-related quality-of-life in the general adult US population
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DOI：
10.1093/pubmed/fdi025
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发表时间：
2005-06-01
影响因子：
4.4
通讯作者：
Lubetkin, EI
中科院分区：
文献类型：
--
作者：
Jia, HM;Lubetkin, EI
美国预防服务工作组最近建议对所有成年患者进行肥胖筛查，部分原因是肥胖与许多慢性疾病之间存在密切联系。然而，肥胖如何影响健康相关的生活质量（HRQL），特别是对于没有任何慢性疾病的人，尚不清楚。方法利用2000年医疗费用调查资料，探讨肥胖与HRQL的关系。根据BMI指数，将年龄为bb0 = 18岁的受访者分为体重过轻、体重正常、超重、ⅰ类肥胖和ⅱ类肥胖。HRQL采用12项短表身心总结评分（分别为PCS-12和MCS-12）和EuroQol EQ- 5d指数和视觉模拟量表（EQ VAS）进行测量。通过多变量回归，调整社会人口统计学和疾病状态，检查肥胖对HRQL的影响。结果调整后HRQL随肥胖程度的增加而降低。重度肥胖者的PCS-12、MCS-12、EQ- 5d指数和EQ VAS得分分别比正常体重者低4.0、1.1、0.073和4.8分，显著低于正常体重者。严重肥胖患者的HRQL下降与糖尿病或高血压患者的HRQL下降相似。中度肥胖或超重的人的HRQL评分也明显较低，尤其是在PCS-12和EQ-5D指数上。体重过轻者的MCS-12和EQ VAS评分也较低。结论：肥胖者的HRQL明显低于体重正常的人，即使没有与肥胖有关的慢性疾病的人也会出现这样的低评分。
Background The US Preventive Services Task Force recently recommended screening all adult patients for obesity due in part to the strong association between obesity and numerous chronic diseases. However, how obesity affects health-related quality-of-life (HRQL), particularly for persons without any chronic diseases, is less clear.Methods The relationship between obesity and HRQL was examined using data from the 2000 Medical Expenditure Panel Survey. Respondents >= 18 years were classified as underweight, normal weight, overweight, class I obesity, and class II obesity based on their BMI. HRQL was measured by the 12-item Short Form physical and mental summary scores (PCS-12 and MCS-12, respectively) and EuroQol EQ-5D index and visual analogue scale (EQ VAS). The impact of obesity on HRQL was examined through multivariate regression, adjusting for sociodemographics and disease status.Results After adjustment, HRQL decreased with increasing level of obesity. Compared to normal weight respondents, persons with severe obesity had significantly lower scores with scores on the PCS-12, MCS-12, EQ-5D index, and EQ VAS being 4.0, 1.1, 0.073, and 4.8 points lower, respectively. Such decrements of HRQL for severe obesity were similar to the decrements seen for diabetes or hypertension. Persons with moderate obesity or who were overweight also had significantly lower HRQL scores, particularly on the PCS-12 and EQ-5D index. Underweight persons also had lower MCS-12 and EQ VAS scores.Conclusions Persons with obesity had significantly lower HRQL than those who were normal weight and such lower scores were seen even for persons without chronic diseases known to be linked to obesity.