Biological synthesis of platinum nanoparticles with apoferritin
Biological synthesis of platinum nanoparticles with apoferritin
复制标题
DOI：
10.1007/s10529-009-0040-3
复制
发表时间：
2009-10-01
影响因子：
2.7
通讯作者：
Wang, X. N.
中科院分区：
文献类型：
--
作者：
Deng, Q. Y.;Yang, B.;Wang, X. N.
报道了一种利用马脾脱铁蛋白（HSAF）合成铂纳米颗粒的新方法。当HSAF与K2 PtCl 6在23 ℃下孵育48小时，随后用NaBH 4还原时，其导致形成球形铂纳米颗粒，尺寸为4.7 +/-A0.9 nm，具有通过透射电子显微镜和能量色散X射线分析证实的窄粒度分布。当初始铂浓度从0.155、0.31、0.465增加到0.62 mM时，脱铁铁蛋白从溶液中去除铂的效率分别为99、99、84和71%。每mM脱铁铁蛋白对铂盐的最大吸收估计为12.7 mmol l（-1）h（-1）。这些结果清楚地表明，HSAF蛋白笼可以成功地作为一个合适的尺寸限制的支持基质的生物合成的铂纳米粒子。
A novel biological method for the synthesis of platinum nanoparticles using the horse spleen apoferritin (HSAF) is reported. When HSAF was incubated with K2PtCl6 at 23A degrees C) for 48 h followed by subsequent reduction with NaBH4 it resulted in the formation of spherical platinum nanoparticles, size 4.7 +/- A 0.9 nm, with narrow particle size distribution confirmed by transmission electron microscopy and energy dispersive X-ray analysis. As the initial platinum concentration increased through 0.155, 0.31, 0.465 to 0.62 mM the efficiency of its removal from solution by the apoferritin was 99, 99, 84 and 71% respectively. The maximum uptake of platinum salt per mM apoferritin was estimated at 12.7 mmol l(-1) h(-1). These results clearly indicate that the HSAF protein cage can successfully serve as a suitable size-constrained support matrix for the biological synthesis of platinum nanoparticles.