REGIONAL DENSITIES OF RETINAL CAPILLARIES AND RETINAL SENSITIVITIES AFTER MACULAR HOLE SURGERY WITH INTERNAL LIMITING MEMBRANE PEELING
REGIONAL DENSITIES OF RETINAL CAPILLARIES AND RETINAL SENSITIVITIES AFTER MACULAR HOLE SURGERY WITH INTERNAL LIMITING MEMBRANE PEELING
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DOI：
10.1097/iae.0000000000002637
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发表时间：
2020-08-01
影响因子：
3.3
通讯作者：
Yamamoto, Shuichi
中科院分区：
文献类型：
--
作者：
Baba, Takayuki;Kakisu, Masato;Yamamoto, Shuichi
目的：采用光学相干断层扫描血管造影术（OCTA）测量特发性黄斑裂孔术后视网膜毛细血管丛的血管密度（VD）。研究方法：回顾性观察病例系列：16例16只眼特发性黄斑裂孔患者行玻璃体切除术联合内界膜剥离术。分别于术前、术后3、6、12个月行视网膜血管造影（OCTA）检查，测量浅层毛细血管丛（SCP）和深层毛细血管丛（DCP）的血管密度（VD），并测量视网膜敏感度（RS）和视网膜内层厚度（IRT）。在四个脑旁象限测量VD、RS和IRT。结果：平均年龄为68.9岁。术后12个月SCP和DCP的VD与RS和IRT均显著相关（SCP和DCP均P < 0.001）。12个月时，SCP和DCP的VD值高于颞象限，RS更敏感，IRT在鼻象限比颞象限厚（P< 0.001，
Purpose: To measure the vascular density (VD) of the retinal capillary plexuses by optical coherence tomography angiography (OCTA) after surgery for an idiopathic macular hole. Methods: Retrospective, observational case series.Sixteen eyes of 16 patients with an idiopathic macular hole underwent vitrectomy with internal limiting membrane peeling. The VDs of the superficial capillary plexus (SCP) and deep capillary plexus (DCP) were determined by OCTA, and the retinal sensitivity (RS) and the inner retinal thickness (IRT) were measured before, and at 3, 6, and 12 months after the surgery. The VD, RS, and IRT were measured at the four parafoveal quadrants. Results: The mean age was 68.9 years. The VDs of the SCP and DCP were significantly correlated with the RS and IRT at 12 months postoperatively (allP< 0.001 for both SCP and DCP). The VDs of the SCP and DCP were higher, the RS more sensitive, and the IRT thicker in the nasal than the temporal quadrant at 12 months (P< 0.001,