REDUCTIVE DECYANATION OF ALPHA-CYANO AND ALPHA-ALKOXYCARBONYL SUBSTITUTED NITRILES PROMOTED BY SAMARIUM(II) IODIDE
REDUCTIVE DECYANATION OF ALPHA-CYANO AND ALPHA-ALKOXYCARBONYL SUBSTITUTED NITRILES PROMOTED BY SAMARIUM(II) IODIDE
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DOI：
10.1016/0040-4039(95)01606-i
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发表时间：
1995-10-16
影响因子：
1.8
通讯作者：
KOH, HY
中科院分区：
文献类型：
--
作者：
KANG, HY;HONG, WS;KOH, HY
碘化钐促进的偕二腈和α-烷氧羰基取代的腈的脱氰反应已被有效地实现。该方法相对于先前已知的使用氢化锡的自由基路线在适用的基底和所采用的反应温度方面具有优势。这种脱氰反应拓宽了腈衍生物的合成应用范围。
Decyanation of geminal dinitriles and alpha-alkoxycarbonyl substituted nitriles promoted by samarium(II) iodide has been efficiently achieved. This method has advantages over the previously known radical route using tin hydride with respect to applicable substrates and the reaction temperature employed. This decyanation could broaden the synthetic applicability of the nitrile derivatives.