Relationship Between Sleep and Obesity: A Cross-sectional and Longitudinal Observational Study of Healthy Adults in Japan
Relationship Between Sleep and Obesity: A Cross-sectional and Longitudinal Observational Study of Healthy Adults in Japan
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睡眠与肥胖之间的关系：针对日本健康成年人的横断面和纵向观察研究
DOI：
10.11320/ningendockitn.nd22-024
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发表时间：
2023
期刊：
影响因子：
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通讯作者：
Nobutake Yamamichi
中科院分区：
文献类型：
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作者：
Mami Takahashi;Takeshi Shimamoto;Atsuko Ozeki;Lumine Matsumoto;Yukari Masuda;Hirotaka Matsuzaki;Eriko Hasumi;Keiko Niimi;Takako Nishikawa;Nobuyuki Sakuma;Naoko Awai;Nobutake Yamamichi
目的：本研究旨在阐明睡眠习惯对日本人肥胖的影响。方法：我们分析了2012-2020年间接受宁恩码头检查的健康人的数据。对5518名年龄为57.5±13.1岁的受试者进行横断面分析，并对1515名年龄为58.2±11.9岁的受试者进行为期6年的纵向追踪分析。结果：青年和老年人的平均睡眠时间为6.4±1.0小时，明显长于中年人。肥胖患病率为25.6%，11.5%的患者在随访期内出现肥胖。在单变量和横断面多变量分析中，睡眠与肥胖显著相关。其他重要因素包括年龄、男性目前吸烟以及女性习惯性饮酒和锻炼。与6小时睡眠组相比，6小时睡眠组男性患肥胖症的几率明显更高，而7小时组和≥8小时组肥胖的几率则更低。在女性中，6小时组的肥胖率更高，而7小时组的肥胖率更低。在纵向多因素分析中，睡眠与肥胖发病的优势比在睡眠6小时组中较高，而在7小时组中较低。结论：男性睡眠时间短与肥胖显著相关，女性也存在类似趋势。因此，大约7小时的睡眠时间在预防成年人肥胖方面可能是有利的。
Objectives: The aim of this study was to elucidate the effects of sleep habits on obesity in Japan.Methods: We analyzed data from healthy people who underwent the “Ningen Dock” examination between 2012 and 2020. A total of 5,518 subjects (age: 57.5±13.1 years) were included in a cross-sectional analysis, and 1,515 (age: 58.2±11.9 years) were followed for 6 years in a longitudinal analysis.Results: The mean sleep duration was 6.4±1.0 hours and was significantly longer in young and elderly people than in middle-aged people. Obesity prevalence was 25.6%, and 11.5% had obesity onset during the follow-up period. In both univariate and cross-sectional multivariate analyses, sleep was significantly associated with obesity. Other significant factors were age, current smoking in males, and habitual drinking and exercise in females. Compared to the 6-hour group, the odds ratio for obesity was significantly higher in males in the< 6-hour sleep group and lower in the 7-hour and≥ 8-hour groups. In females, there were tendencies towards higher obesity rates in the< 6-hour group, and lower rates in the 7-hour group. In the longitudinal multivariate analysis, the odds ratio for sleep in relation to obesity onset tended to be higher in the< 6-hour group and lower in the 7-hour group.Conclusions: Short sleep duration was significantly correlated with obesity in males, and a similar tendency was found in females. Therefore, a sleep duration of approximately 7 hours may be advantageous in terms of obesity prevention in adults.