Platelet production and platelet destruction: assessing mechanisms of treatment effect in immune thrombocytopenia

Platelet production and platelet destruction: assessing mechanisms of treatment effect in immune thrombocytopenia
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DOI:
10.1182/blood-2010-11-321398
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发表时间:
2011-05-26
期刊:
影响因子:
20.3
通讯作者:
Bussel, James B.
Bussel, James B.
中科院分区:
医学1区
文献类型:
--
作者:
Barsam, Sarah J.;Psaila, Bethan;Bussel, James B.

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本研究探讨未成熟血小板分数(IPF)在评价免疫性血小板减少症(ITP)治疗效果中的作用。在Sys-Mex XE2100全自动分析仪上测定IPF。ITP患者的平均绝对IPF(A-IPF)低于健康对照组(3.2vs7.8×10(9)/L,P
This study investigated the immature platelet fraction (IPF) in assessing treatment effects in immune thrombocytopenia (ITP). IPF was measured on the Sys-mex XE2100 autoanalyzer. The mean absolute-IPF (A-IPF) was lower for ITP patients than for healthy controls (3.2 vs 7.8 x 10(9)/L, P