Study of interaction between water-soluble collagen and carboxymethyl cellulose in neutral aqueous solution.
Study of interaction between water-soluble collagen and carboxymethyl cellulose in neutral aqueous solution.
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DOI：
10.1016/j.carbpol.2015.10.098
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发表时间：
2016-02
影响因子：
11.2
通讯作者：
Min Zhang;Cuicui Ding;Junhui Yang;Shan Lin;Lihui Chen;Liulian Huang
中科院分区：
文献类型：
--
作者：
Min Zhang;Cuicui Ding;Junhui Yang;Shan Lin;Lihui Chen;Liulian Huang
研究了琥珀酰化胶原（SC）与羧甲基纤维素（CMC）在中性溶液（pH = 6.9）中的相互作用，为组织工程和化妆品等领域的研究提供参考。粘度测定结果表明，当CMC ≤ 50%时，SC和CMC分子可能相容。当CMC含量≤ 50%时，转变温度（Tm）和热容变化（ΔCp）均增大，而当CMC含量进一步增大时，Tm和Δ Cp均减小。二维傅里叶变换红外光谱分析证实了SC与CMC之间存在氢键和静电相互作用，当CMC含量≤ 50%时，氢键作用起主要作用，而随着CMC含量的增加，静电作用逐渐占主导地位。原子力显微镜观察到了CMC诱导SC聚集的变化。
The interactions of succinylated collagen (SC) and carboxymethyl cellulose (CMC) in neutral solutions (pH ∼ 6.9) were investigated, which could provide information for the fields of tissue engineering and cosmetics. According to the results from viscometric measurements, the SC and CMC molecules were possibly compatible as CMC ≤ 50%. Ultrasensitive microcalorimetry reflected the increase in the values of transition temperature (Tm) and heat capacity change (ΔCp) as CMC ≤ 50%, while both of them decreased as the CMC content further increased. Two-dimensional Fourier transform infrared spectroscopy analysis confirmed the hydrogen bonding and electrostatic interactions between SC and CMC, and the hydrogen bonding interaction played a key role as CMC ≤ 50%, while electrostatic interaction became predominant as more CMC was added. Atomic force morphology revealed the changes in the aggregation of SC induced by the addition of CMC.