Investigation of mood-congruent false and true memory recognition in depression

Investigation of mood-congruent false and true memory recognition in depression
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DOI:
10.1002/da.20054
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发表时间:
2005-01-01
影响因子:
7.4
通讯作者:
Brassen, S
Brassen, S
中科院分区:
医学1区
文献类型:
--
作者:
Moritz, S;Gläscher, J;Brassen, S

文献摘要

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本研究探讨了抑郁症患者情绪一致性假记忆和真实记忆识别的程度。一组25名抑郁症患者和28名健康对照者完成了迪斯-罗迪格·麦克德莫特任务的一个变体。研究人员按顺序向参与者朗读了四个列表,然后进行了识别任务。每个列表中的单词都与一个中心但未被提及的主题词相关联,这些主题词要么与抑郁相关(即孤独),要么与错觉相关(背叛),要么积极(假期),要么中性(窗口)。虽然它被期望复制抑郁症中传统的情绪一致效应(更好地识别抑郁相关的项目),但现有的文献并没有允许对抑郁症中情绪一致错误识别的程度做出强有力的预测。结果显示,抑郁症患者学习情绪化材料的能力与健康参与者一样好,但遗忘中性材料的能力明显更强。传统的情绪一致记忆偏差没有被发现,但与健康对照相比,抑郁症患者对带有情绪色彩的词语,尤其是与抑郁相关的词语,有更多的错误识别错误。结果证实,抑郁症患者倾向于情感材料。讨论了预期情绪一致记忆偏差不存在的原因。作者建议研究者和临床医生应更加重视情绪一致性错误回忆,因为它可能会破坏抑郁症患者自传体报告的有效性,并可能代表该疾病的维持因素。(c) 2005 Wiley-Liss, Inc。
The present study investigated the extent of mood-congruent false and true memory recognition in depression. A group of 25 patients with depression and 28 healthy controls completed a variant of the Deese-Roediger McDermott task. Four lists were read to participants in sequence, followed by a recognition task. The words in each list were associated with a central but unmentioned theme word that was either depression-relevant (i.e., loneliness), delusion-relevant (betrayal), positive (holidays), or neutral (window). Whereas it was expected to replicate the conventional mood-congruent effect in depression (better recognition of depression-relevant items), the available literature did not allow strong predictions to be made on the extent of mood-congruent false recognition in depression. Results showed that depressed patients learned emotionally charged material equally well as healthy participants but forgot significantly more neutral material. A conventional mood-congruent memory bias was not found, but relative to healthy controls, patients with depression committed more false recognition errors for emotionally charged words, particularly for depression-relevant items. The results confirm that depressed patients are biased toward emotional material. Reasons for the absence of the expected mood-congruent memory bias are discussed. It is suggested that researchers as well as clinicians should pay more attention to mood-congruent false recollection, because it may undermine the validity of autobiographic reports in depressive patients and may represent a maintenance factor for the disorder. (c) 2005 Wiley-Liss, Inc.