Pneumonia and Empyema Caused by Streptococcus intermedius that Shows the Diagnostic Importance of Evaluating the Microbiota in the Lower Respiratory Tract

Pneumonia and Empyema Caused by Streptococcus intermedius that Shows the Diagnostic Importance of Evaluating the Microbiota in the Lower Respiratory Tract
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DOI:
10.2169/internalmedicine.53.0971
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发表时间:
2014-01-01
期刊:
影响因子:
1.2
通讯作者:
Mukae, Hiroshi
Mukae, Hiroshi
中科院分区:
医学4区
文献类型:
--
作者:
Noguchi, Shingo;Yatera, Kazuhiro;Mukae, Hiroshi

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链球菌群(链球菌、链球菌、中间链球菌)是细菌性肺炎、肺脓肿和脓胸的重要病原菌。然而,这组细菌主要是口腔驻留细菌,不能在普通好氧培养基上显著生长。我们经历了一例由中间链球菌引起的肺炎和脓胸,通过对支气管肺泡灌洗液和胸腔积液进行16S rRNA基因测序分析发现,但没有痰。即使在应用分子方法时,痰样本有时也不适合识别下呼吸道感染的病原体。
The bacterial species in the Streptococcus anginosus group (S. constellatus, S. anginosus, S. intermedius) are important causative pathogens of bacterial pneumonia, pulmonary abscesses and empyema. However, the bacteria in this group are primarily oral resident bacteria and unable to grow significantly on ordinary aerobic culture media. We experienced a case of pneumonia and empyema caused by Streptococcus intermedius detected using a 16S rRNA gene sequencing analysis of bronchoalveolar lavage fluid and pleural effusion, but not sputum. Even when applying the molecular method, sputum samples are occasionally unsuitable for identifying the causative pathogens of lower respiratory tract infections.