Asymptomatic Dengue Virus Infections, Cambodia, 2012-2013
Asymptomatic Dengue Virus Infections, Cambodia, 2012-2013
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DOI：
10.3201/eid2507.181794
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发表时间：
2019-07-01
影响因子：
11.8
通讯作者：
Tarantola, Arnaud
中科院分区：
文献类型：
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作者：
Ly, Sowath;Fortas, Camille;Tarantola, Arnaud
2012年至2013年期间，我们对柬埔寨磅湛省农村地区的登革热病毒（DENV）以及无症状登革热病毒感染情况进行了调查。我们针对通过医院和村庄监测确定的149例登革热指示病例，在其家庭内部及周边开展了病灶周边调查。我们使用非结构蛋白1快速检测法对0.5 - 30岁的参与者进行检测，并通过定量逆转录聚合酶链反应或非结构蛋白1捕获酶联免疫吸附测定法确认登革热病毒感染情况。我们使用多变量泊松回归分析来探究参与者的登革热病毒感染状况与家庭特征之间的联系。在7960名研究参与者中，346人（4.4%）感染了登革热病毒，其中302人（87.3%）年龄小于15岁，225人（65.0%）……
We investigated dengue virus (DENV) and asymptomatic DENV infections in rural villages of Kampong Cham Province, Cambodia, during 2012 and 2013. We conducted perifocal investigations in and around households for 149 DENV index cases identified through hospital and village surveillance. We tested participants 0.5-30 years of age by using nonstructural 1 rapid tests and confirmed DENV infections using quantitative reverse transcription PCR or non-structural 1-capture ELISA. We used multivariable Poisson regressions to explore links between participants' DENV infection status and household characteristics. Of 7,960 study participants, 346 (4.4%) were infected with DENV, among whom 302 (87.3%) were < 15 years of age and 225 (65.0%) were