The 2D IR responses of amide and carbonyl modes in water cannot be described by Gaussian frequency fluctuations
The 2D IR responses of amide and carbonyl modes in water cannot be described by Gaussian frequency fluctuations
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DOI：
10.1021/jp074267x
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发表时间：
2007-08-23
影响因子：
3.3
通讯作者：
Hochstrasser, Robin M.
中科院分区：
文献类型：
--
作者：
Kim, Yung Sam;Hochstrasser, Robin M.
二维（2D）红外光谱形状的水酰胺-I '或羰基具有明显的单一频带是不是那些预测的高斯频率波动。他们的人口演化暴露离散分布进行皮秒时间尺度交换。能量转移到其他模式提供了一个清晰的视图，这在很大程度上是由于交换水配置的基础结构。结果表明，新的方法来检查蛋白结合水的残留水平。
The two-dimensional (2D) IR spectral shapes seen for aqueous amide-I ' or carbonyls having apparently single bands are not those predicted by Gaussian frequency fluctuations. Their population evolution exposes discrete distributions undergoing picosecond time scale exchange. The energy transfer to other modes provides a clear view of this underlying structure, which is largely attributed to exchanging water configurations. The results suggest new approaches to examine protein-bound water at the residue level.