Culture Conditions of Marine Bacterium SCRC-2738 for the Production of Eicosapentaenoic Acid(EPA).
Culture Conditions of Marine Bacterium SCRC-2738 for the Production of Eicosapentaenoic Acid(EPA).
复制标题
用于生产二十碳五烯酸 (EPA) 的海洋细菌 SCRC-2738 的培养条件。
DOI：
10.2331/suisan.58.323
复制
发表时间：
1992
影响因子：
0.4
通讯作者：
K. Takada
中科院分区：
文献类型：
--
作者：
N. Suzuki;K. Yazawa;Kazuo Watanabe;Yukari Akahori;C. Ishikawa;K. Kondo;K. Takada
研究了利用产EPA的海洋细菌SCRC-2738工业化生产二十碳五烯酸（EPA）的工艺。采用16l小罐发酵罐试验了在培养温度和人工海水浓度等条件下的EPA产量，然后采用200l小罐发酵罐进行了EPA的中试生产。在该细菌的指数生长阶段，EPA产量在8°C时增加到376.4mg/l，而在15°C时为145.0mg/l。在50%至100%的人工海水中，75%的培养基中EPA产量最高。利用200l罐发酵罐进行的进一步研究表明，利用这种细菌工业化生产EPA是可能的。
Industrial production of eicosapentaenoic acid (EPA) by using EPA-producting marine bacterium SCRC-2738 was examined. EPA production under some conditions such as incubation temperature and concentration of artificial sea water was tested using a 16l mini-jar fermentor and then pilot scale production of EPA was also performed using a 200l jar fermentor. In the exponential growth phase of this bacterium, EPA production was increased to 376.4mg/l at 8°C compared to 145.0mg/l at 15°C. The highest EPA production was seen in a medium composed of 75% artificial sea water between 50 and 100%. Further study using a 200l jar fermentor suggested the possibility of industrial production of EPA using this bacterium.