Metal-free allylation of electron-rich heteroaryl boronic acids with allylic alcohols
Metal-free allylation of electron-rich heteroaryl boronic acids with allylic alcohols
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富电子杂芳基硼酸与烯丙醇的无金属烯丙基化
DOI：
10.1016/j.tet.2016.02.047
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发表时间：
2016-04-14
期刊：
影响因子：
2.1
通讯作者：
Cheng, Liang
中科院分区：
文献类型：
--
作者：
Li, Xue-Dong;Xie, Li-Jun;Cheng, Liang
本文介绍了一种简便的无催化剂条件下杂芳基硼酸与烯丙醇的区域选择性交叉偶联反应。所开发的程序是简单的，在外部氧化剂和无金属的条件下工作，并证明是非常普遍的具有前所未有的邻位选择性。这种方法代表了硼酸邻位官能化的极少数实例之一。(C)2016爱思唯尔有限公司版权所有
A convenient and regioselective cross-coupling of heteroaryl boronic acids with allylic alcohols under catalyst-free reaction conditions is described. The developed procedure is simple, works under external oxidant- and metal-free conditions, and proves to be very general with an unprecedented ortho-selectivity. This approach represents one of the very few examples of ortho-functionalization of boronic acids. (C) 2016 Elsevier Ltd. All rights reserved.