A highly efficient solvent-free synthesis of dihydropyrimidinones catalyzed by zinc chloride
A highly efficient solvent-free synthesis of dihydropyrimidinones catalyzed by zinc chloride
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DOI：
10.1055/s-2004-822331
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发表时间：
2004-05-06
影响因子：
2.6
通讯作者：
Li, RT
中科院分区：
文献类型：
--
作者：
Sun, Q;Wang, YQ;Li, RT
二氢嘧啶酮由氯化锌（20mol%）催化的醛、1，3-二羰基化合物和脲或硫脲的Biginelli缩合反应在80 ℃下在短时间内在无溶剂条件下以高产率制备。
Dihydropyrimidinones are prepared from zinc chloride (20 mol%) catalyzed Biginelli condensation of an aldehyde, 1,3-dicarbonyl compounds and urea or thiourea at 80 degreesC for short time under solvent-free conditions in high yields.