Comparison study of hydrolytic degradation behaviors between α′- and α-poly(l-lactide)
Comparison study of hydrolytic degradation behaviors between α′- and α-poly(l-lactide)
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α-聚丙交酯和α-聚丙交酯水解降解行为的比较研究
DOI：
10.1016/j.polymdegradstab.2017.12.014
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发表时间：
2018-02
影响因子：
5.9
通讯作者：
Yong Wang
中科院分区：
文献类型：
--
作者：
Nan Zhang;Xu Yu;Jin Duan;Jing-hui Yang;Ting Huang;Xiao-dong Qi;Yong Wang
作为典型的多晶型聚合物之一，聚(L-丙交酯)(PLLA)表现出物理/化学性能对晶体结构的极大依赖性。在这项工作中，首次研究了水解过程中PLLA的水解降解行为对晶型（分别为α'-和α-型）和结晶度（分别低于30wt％和高于45％）的依赖性。为了赋予样品不同的晶型和结晶度，对非晶态PLLA样品在不同条件下进行退火。通过各种表征方法研究了样品的晶体结构。水解降解测量在 50°C 的蒸馏水中进行。具体来说，通过紫外-可见分光光度计检测介质中水解产物的浓度来定性分析样品的水解降解程度。结果表明，对于结晶度较低（<30wt%）的样品，在水解降解过程的初始阶段，与α'型但结晶度较高的样品相比，α型但结晶度较低的样品降解更为严重。而在水解降解过程的后期，α'型样品的水解作用更为严重。然而，对于结晶度较高（>45%）的样品，α'型样品在整个降解过程中表现出更严重的水解作用。还测量了样品的微观结构演化，结果表明PLLA样品的晶体结构演化主要由水解降解前样品的初始晶体结构决定。
As one of the typical polymorphic polymers, poly(l-lactide) (PLLA) exhibits great dependences of physical/chemical performances on the crystalline structures. In this work, the dependences of hydrolytic degradation behavior of PLLA on the crystal form (α′- and α-form, respectively) and crystallinity (lower than 30 wt% and higher than 45%, respectively) during the hydrolysis process were investigated for the first time. To endow the samples with different crystal forms and crystallinities, the amorphous PLLA samples were annealed under different conditions. The crystalline structures of the samples were investigated through various characterization methods. The hydrolytic degradation measurements were carried out at 50 °C in distilled water. Specifically, the degree of the hydrolytic degradation of samples was qualitatively analyzed through detecting the concentration of hydrolysate in the medium using UV–Vis spectroscope. The results showed that for the samples with relatively low crystallinity (<30 wt%), in the initial stage of the hydrolytic degradation process, sample with α-form but lower crystallinity exhibited more serious degradation compared with the sample with α′-form but higher crystallinity. While in the later stage of the hydrolytic degradation process, sample with α′-form exhibits more serious hydrolysis. However, for the samples with relatively high crystallinity (>45%), sample with α′-form exhibits more serious hydrolysis during the whole degradation process. The microstructure evolution of samples was also measured and the results showed that the crystalline structure evolution of the PLLA samples was mainly determined by the initial crystal structures of samples before hydrolytic degradation.
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影响因子：
3
作者：
H. Tsuji;M. Sawada
通讯作者：
H. Tsuji;M. Sawada
影响因子：
4.6
作者：
M. Yasuniwa;Kazunari Sakamo;Y. Ono;Wataru Kawahara
通讯作者：
M. Yasuniwa;Kazunari Sakamo;Y. Ono;Wataru Kawahara
影响因子：
3
作者：
Tsuji, H;Nakahara, K
通讯作者：
Nakahara, K
影响因子：
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作者：
Ouchiar, Saadia;Stoclet, Gregory;Gloaguen, Vincent
通讯作者：
Gloaguen, Vincent
影响因子：
5.9
作者：
Gorrasi, Giuliana;Pantani, Roberto
通讯作者：
Pantani, Roberto