Weight status and differences in mobility performance, pain symptoms, and physical activity in older, knee osteoarthritis patients.
Weight status and differences in mobility performance, pain symptoms, and physical activity in older, knee osteoarthritis patients.
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DOI：
10.1155/2014/375909
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发表时间：
2014
期刊：
影响因子：
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通讯作者：
Rejeski WJ
中科院分区：
文献类型：
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作者：
Garver MJ;Focht BC;Dials J;Rose M;Lucas AR;Devor ST;Emery CF;Hackshaw KV;Rejeski WJ
膝关节骨关节炎（OA）是美国成年人功能障碍的主要原因。肥胖是OA的一个独立危险因素。虽然研究强调了肥胖在OA-身体功能关系中的作用，但体重状况对老年膝关节OA患者显著的身体、健康和疼痛指标的影响程度尚不清楚。本研究的主要目的是评估活动能力（爬楼梯和400米步行），活动相关的自我效能，疼痛症状（WOMAC）和加速度计确定的身体活动（PA）作为体重状态的函数的措施的差异。进行协方差分析以检查因变量的差异。肥胖III级患者的表现优于他们的同行几乎每一个措施的流动性，流动性相关的自我效能感，并评估疼痛症状。这些结果在其他体重比较中没有差异。正常体重受试者在PA的大多数指标（参与中度或更高PA和每周总步数）上优于I、II和III类受试者。此外，超重参与者的每周总步数优于肥胖II级参与者，肥胖I级参与者的每周总步数优于肥胖II级和III级参与者。总的来说，这些发现强调了在相关OA结局中观察到的有意义的差异作为体重水平增加的函数。
Knee osteoarthritis (OA) is a leading cause of functional disability among American adults. Obesity is a strong independent risk factor for OA. While research emphasizes the role of obesity in the OA-physical function relationship, the extent to which weight status impacts salient physical, health, and pain measures in older, knee OA patients is not well delineated. The primary aim of this study was to assess differences in mobility performance (stair climb and 400-meter walk), mobility-related self-efficacy, pain symptoms (WOMAC), and measures of accelerometer-determined physical activity (PA) as a function of weight status. Analysis of covariance was conducted to examine differences on the dependent variables. Obese class III patients were outperformed by their counterparts on nearly every measure of mobility, mobility-related self-efficacy, and the assessment of pain symptoms. These outcomes did not differ among other weight comparisons. Normal weight subjects outperformed classes I, II, and III counterparts on most measures of PA (engagement in moderate or greater PA and total weekly steps). Additionally, overweight participants outperformed obese class II participants and obese class I participants outperformed obese classes II and III participants on total weekly steps. Collectively, these findings underscore the meaningful differences observed in relevant OA outcomes as a function of increasing levels of body weight.