Ground-Glass Nodules on Chest CT as Imaging Biomarkers in the Management of Lung Adenocarcinoma
Ground-Glass Nodules on Chest CT as Imaging Biomarkers in the Management of Lung Adenocarcinoma
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DOI：
10.2214/ajr.10.5813
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发表时间：
2011-03-01
影响因子：
5
通讯作者：
Lee, Hyun Ju
中科院分区：
文献类型：
--
作者：
Goo, Jin Mo;Park, Chang Min;Lee, Hyun Ju
OBJECTIVE.本文就肺腺癌中磨玻璃样结节（GGN）的临床意义进行综述。GGN可作为影像学生物标志物，代表腺癌组织学中细支气管肺泡癌成分，并指示肺腺癌患者的预后较好。GGN的演变反映了腺癌的多步骤进展。尽管GGN的恶性可能性很高，但在GGN的管理中应考虑过度诊断的可能性。
OBJECTIVE. The purpose of this article is to review the clinical significance of ground-glass nodules (GGNs) in the management of lung adenocarcinoma.CONCLUSION. GGNs can serve as imaging biomarkers that represent the bronchioloalveolar carcinoma component in adenocarcinoma on histology and indicate a better prognosis in patients with lung adenocarcinoma. The evolution of GGNs reflects the multistep progression of adenocarcinoma. Despite the high probability of malignancy of GGNs, the possibility of overdiagnosis should be considered in the management of GGNs.