Physiological, biochemical and molecular aspects of mitochondrial complex I in plants

Physiological, biochemical and molecular aspects of mitochondrial complex I in plants
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DOI:
10.1016/s0005-2728(98)00021-8
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发表时间:
1998-05-06
影响因子:
4.3
通讯作者:
Grohmann, L
Grohmann, L
中科院分区:
生物学2区
文献类型:
--
作者:
Rasmusson, AG;Heiser, V;Grohmann, L

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植物线粒体呼吸复合体I的生理功能、生化特性和分子结构已被广泛研究。在呼吸链复合体中,I是基质NADH中低势电子的主要进入门,还原泛醌并利用释放的能量将质子泵过内膜。植物复合体I在其他几种NAD(P)H脱氢酶的背景下是活跃的,这些脱氢酶不参与质子泵,但允许并建立几种不同的电子从NAD(P)H到泛醌的穿梭途径,鉴定相应的分子结构,即不同NADH脱氢酶的蛋白质和基因,将有助于更详细地研究植物线粒体中这个相互作用的调控网络。本文综述了目前关于植物中复合体I的结构以及编码该复合体各亚单位的线粒体和核基因的知识。(C)1998年爱思唯尔科学公司。
Respiratory complex I of plant mitochondria has to date been investigated with respect to physiological function, biochemical properties and molecular structure. In the respiratory chain complex I is the major entry gate for low potential electrons from matrix NADH, reducing ubiquinone and utilizing the released energy to pump protons across the inner membrane. Plant complex I is active against a background of several other NAD(P)H dehydrogenases, which do not contribute in proton pumping, but permit and establish several different routes of shuttling electrons from NAD(P)H to ubiquinone, Identification of the corresponding molecular structures, that is the proteins and genes of the different NADH dehydrogenases, will allow more detailed studies of this interactive regulatory network in plant mitochondria. Present knowledge of the structure of complex I and the respective mitochondrial and nuclear genes encoding various subunits of this complex in plants is summarized here. (C) 1998 Elsevier Science B.V.