The San Diego definition of SIDS: practical application and comparison with the GeSID classification

The San Diego definition of SIDS: practical application and comparison with the GeSID classification
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DOI:
10.1007/s00414-005-0043-0
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发表时间:
2006-11-01
影响因子:
2.1
通讯作者:
Vennemann, M.
Vennemann, M.
中科院分区:
医学3区
文献类型:
--
作者:
Bajanowski, T.;Brinkmann, B.;Vennemann, M.

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婴儿猝死综合征(SIDS)一词的新定义和圣地亚哥引入的病例亚分类标准已被用于对德国SIDS研究(GeSID)登记的前100例婴儿猝死和意外死亡的连续病例进行重新分类。虽然在圣地亚哥定义的一般和分层部分中必须考虑30个不同的变量,但它是实用的,特别是作为进行科学研究的国际标准。圣地亚哥定义和GeSID分类的比较表明,方法相似,但所用标准不同。然而,分类为SIDS和临界SIDS的病例数量相似(圣地亚哥n=69,GeSID n=74)。任何病例均不符合圣地亚哥定义的SIDS IA标准,因为代谢筛查和玻璃体化学未纳入GeSID研究方案。圣地亚哥定义的一个重要优点是引入了未分类的婴儿猝死类别,其中包括未进行尸检的病例。这表明这些病例不能归类为小岛屿发展中国家。最后,我们建议普遍接受和使用圣地亚哥小岛屿发展中国家的定义。
The new definition of the term sudden infant death syndrome (SIDS) and the criteria introduced in San Diego for the subclassification of cases have been used to re-classify the first 100 consecutive cases of sudden and unexpected infant deaths that were registered with the German SIDS study (GeSID). Although there are 30 different variables that have to be considered in the general and stratified sections of the San Diego definition, it is practical, in particular, as an international standard to perform scientific studies. The comparison of the San Diego definition and the classification used for GeSID shows similarities in the methods but differences in the criteria used. Nevertheless, the numbers of cases classified as SIDS and borderline SIDS are similar (San Diego n=69, GeSID n=74). The SIDS IA criteria of the San Diego definition were not fulfilled by any case because metabolic screening and vitreous chemistry were not included in the GeSID investigation scheme. An important advantage of the San Diego definition is the introduction of the category of unclassified sudden infant death, which includes cases for which no autopsy was performed. This demonstrates that such cases cannot be classified as SIDS. In conclusion, we recommend the universal acceptance and use of the San Diego SIDS definition.