Gastric acid secretion: Changes during a century
Gastric acid secretion: Changes during a century
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DOI：
10.1016/j.bpg.2014.10.006
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发表时间：
2014-12-01
影响因子：
3.2
通讯作者：
Goni, Elisabetta
中科院分区：
文献类型：
--
作者：
Di Mario, Francesco;Goni, Elisabetta
上个世纪胃生理学知识的进步是数十年来该领域最令人兴奋和最重要的进展。本次演讲的目的是全面回顾有关该主题的最新文献，以突出胃生理学领域的里程碑，特别是在胃酸分泌、胃病理生理学、胃酸相关疾病和胃酸调节药物的使用方面。此外，在21世纪，流行病学发生了许多变化，幽门螺杆菌感染和胃癌减少，而胃食管反流病增加，相关的pomp质子抑制剂广泛使用增加。 (C) 2014 Elsevier Ltd. 保留所有权利。
The advances in knowledge of gastric physiology within the past century have been the most exciting and important in this area of interest for many decades.The aim of this presentation consists of a comprehensive review of the extensive recent literature on this topic in order to highlight milestones in the field of gastric physiology, in particular in gastric acid secretion, gastric pathophysiology, acid-related diseases and use of acid regulatory drugs. Moreover, in the 21st century there have been many epidemiologic changes as well as a decrease of Helicobacter pylori infection and gastric cancer together with an increase of gastroesophageal reflux disease and the related increase of pomp proton inhibitor wide use. (C) 2014 Elsevier Ltd. All rights reserved.