A neonate with Down's syndrome and transient abnormal myelopoiesis: serial blood and bone marrow studies.
A neonate with Down's syndrome and transient abnormal myelopoiesis: serial blood and bone marrow studies.
复制标题
患有唐氏综合症和短暂性骨髓生成异常的新生儿：连续血液和骨髓研究。
作者：
Takeshi Nagao;Takeshi Nagao;Beatrice C. Lampkin;Beatrice C. Lampkin;George Hug;George Hug
对一名患有唐氏综合症的男婴一岁时的血液和骨髓进行了观察。4日龄时，每立方毫米有36500个成髓细胞。血液中，骨髓中有10.8%的成髓细胞。最初，病人似乎患有急性髓母细胞白血病。然而，他的临床过程、骨髓细胞群的动力学和电镜研究表明，他没有急性白血病。
Observations were made of the blood and bone marrow of a male infant with Down’s syndrome during the first year of life. At 4 days of age there were 36,500 myeloblasts/cu.mm. in the blood and 10.8 per cent myeloblasts in the marrow. Initially it appeared the patient had acute myeloblastic leukemia. However, the clinical course and kinetic and electron microscopic studies of his bone marrow cell population indicate he did not have acute leukemia.