Acute lung injury and bacterial infection
Acute lung injury and bacterial infection
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DOI：
10.1016/j.ccm.2004.10.014
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发表时间：
2005-03-01
影响因子：
5.7
通讯作者：
Ricard, JD
中科院分区：
文献类型：
--
作者：
Dreyfuss, D;Ricard, JD
急性肺损伤与细菌感染之间的关系复杂。事实上，败血症，特别是肺炎，是急性肺损伤的主要原因。肺部细菌重叠感染是急性肺损伤的常见并发症。由于宿主防御能力受损和机械通气时间延长，超过三分之一的急性呼吸窘迫综合征患者患上与呼吸机相关的肺炎，大多数情况下病原体具有耐药性。这一并发症使机械通气的时间增加了一倍以上，但似乎并没有增加死亡率。
The relationships between acute lung injury and bacterial infection are complex. Indeed, sepsis and in particular pneumonia are leading causes of acute lung injury. Bacterial superinfection of the lung is a frequent complication of acute lung injury. Because of impaired host defenses and prolonged mechanical ventilation, more than one third of patients with the acute respiratory distress syndrome acquire ventilator-associated pneumonia, with resistant pathogens in most instances. This complicatio is responsible for more than a doubling of the time on mechanical ventilation but does not seem to increase mortality.