Effect of cytokine and pharmacogenomic genetic polymorphisms in transplantation.

Effect of cytokine and pharmacogenomic genetic polymorphisms in transplantation.
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细胞因子和药物基因组遗传多态性在移植中的影响。

DOI:
10.1016/j.coi.2008.08.002
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发表时间:
2008
影响因子:
7
通讯作者:
Zeevi,Adriana
Zeevi,Adriana
中科院分区:
医学2区
文献类型:
--
作者:
Girnita,DianaM;Burckart,Gilbert;Zeevi,Adriana

文献摘要

相似文献

Consolidating the information that we have on pharmacogenetics and on cytokine genetics to produce patient-oriented individualized drug regimens is an important challenge in transplantation medicine. Using a multi-variant approach based on genetic profile and other relevant clinical factors a score system may be developed to predict the severity of rejection, infection, or other complications associated with transplantation. The ultimate goal of these studies is to improve patient outcome through individualized drug regimens.