Design and Synthesis of a Universal Antigen to Detect Brucellosis
Design and Synthesis of a Universal Antigen to Detect Brucellosis
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DOI：
10.1002/anie.201302303
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发表时间：
2013-07-08
影响因子：
16.6
通讯作者：
Bundle, David R.
中科院分区：
文献类型：
--
作者：
Guiard, Julie;Paszkiewicz, Eugenia;Bundle, David R.
升级诊断：已经制备了一种通用抗原，用于检测由表达光滑脂多糖的任何布鲁氏菌属种引起的布鲁氏菌病。这种包含布鲁氏菌A-和M-抗原决定簇的九糖仅可通过化学合成获得。
Upgrading diagnostics: A universal antigen has been prepared for the detection of brucellosis caused by any Brucella species that express a smooth lipopolysaccharide. This nonasaccharide, which encompasses Brucella A‐and M‐antigenic determinants, is uniquely available only by chemical synthesis.