Two-stepping through time: mammals and viruses.
Two-stepping through time: mammals and viruses.
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DOI：
10.1016/j.tim.2011.03.006
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发表时间：
2011-06
影响因子：
15.9
通讯作者：
Sawyer SL
中科院分区：
文献类型：
--
作者：
Meyerson NR;Sawyer SL
最近的研究发现，古代病毒基因组以化石形式保存在不同的动物基因组中。这些化石揭示了许多哺乳动物病毒家族比以前认为的更古老、更普遍。病毒与其宿主之间的长期相互作用常常发展成基因军备竞赛，双方不断争夺进化优势。很难想象哺乳动物宿主如何在漫长的时间里与快速进化的病毒进行进化竞赛，因为它们的进化速度要慢得多。然而，最近的数据已经开始揭示缓慢进化的宿主的进化策略。我们回顾了这些数据，并提出了一种修改后的军备竞赛模型，其中病毒的进化可能性相对受到限制。这样的模型可以更准确地预测病毒的进化。
Recent studies have identified ancient virus genomes preserved as fossils within diverse animal genomes. These fossils have led to the revelation that a broad range of mammalian virus families are older and more ubiquitous than previously appreciated. Long-term interactions between viruses and their hosts often develop into genetic arms races, where both parties continually jockey for evolutionary dominance. It is difficult to imagine how mammalian hosts have kept pace in the evolutionary race against rapidly evolving viruses over large expanses of time, given their much slower evolutionary rates. However, recent data has begun to reveal the evolutionary strategy of slowly-evolving hosts. We review these data, and suggest a modified arms race model where the evolutionary possibilities of viruses are relatively constrained. Such a model could allow more accurate forecasting of virus evolution.
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影响因子：
6.7
作者：
Delport, Wayne;Scheffler, Konrad;Seoighe, Cathal
通讯作者：
Seoighe, Cathal
影响因子：
56.9
作者：
Carrington, M;Nelson, GW;O'Brien, SJ
通讯作者：
O'Brien, SJ
DOI：
10.1126/science.1187816
发表时间：
2010-06-04
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Bloom JD;Gong LI;Baltimore D
通讯作者：
Baltimore D
DOI：
10.1084/jem.188.11.2057
发表时间：
1998-12-07
期刊：
The Journal of experimental medicine
影响因子：
--
作者：
Chen Z;Kwon D;Jin Z;Monard S;Telfer P;Jones MS;Lu CY;Aguilar RF;Ho DD;Marx PA
通讯作者：
Marx PA
影响因子：
64.8
作者：
Elde NC;Child SJ;Geballe AP;Malik HS
通讯作者：
Malik HS