Long-Term Bilateral Neuromuscular Function and Knee Osteoarthritis after Anterior Cruciate Ligament Reconstruction.
Long-Term Bilateral Neuromuscular Function and Knee Osteoarthritis after Anterior Cruciate Ligament Reconstruction.
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DOI：
10.3390/bioengineering10070812
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发表时间：
2023-07-06
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神经肌肉功能被认为是前交叉韧带（ACL）重建（ACLR）患者创伤后骨关节炎（PTOA）风险的因素之一，但需要敏感和易于使用的工具来辨别复杂的肌肉激活策略是有益的还是不适应的。使用肌电图（EMG）信号分析技术结合机器学习方法，我们试图：(1)确定ACLR肌肉活动模式是否与健康对照不同，(2)探索患者结果测量（大腿肌肉周长、膝盖松弛度、跳跃距离和活动水平）的组合通过磁共振成像（MRI）预测ACLR患者骨关节炎变化的程度。11例术后10-15年的ACLR患者和12名健康对照者在记录双侧下肢肌肉肌电图的同时进行了跳活动。基于MRI评估骨关节炎。ACLR肌肉活动模式是双侧对称的，与健康对照不同，表明存在全局适应策略。同侧大腿肌围较小是较差MRI评分的最强预测因子。我们的肌电图分析方法能够检测到有意义的神经肌肉差异，这些差异最终可能与大腿肌肉周长有关，这为进一步研究肌肉激活模式与pta风险之间的直接联系提供了基础。
Neuromuscular function is thought to contribute to posttraumatic osteoarthritis (PTOA) risk in anterior cruciate ligament (ACL)-reconstructed (ACLR) patients, but sensitive and easy-to-use tools are needed to discern whether complex muscle activation strategies are beneficial or maladaptive. Using an electromyography (EMG) signal analysis technique coupled with a machine learning approach, we sought to: (1) identify whether ACLR muscle activity patterns differed from those of healthy controls, and (2) explore which combination of patient outcome measures (thigh muscle girth, knee laxity, hop distance, and activity level) predicted the extent of osteoarthritic changes via magnetic resonance imaging (MRI) in ACLR patients. Eleven ACLR patients 10–15 years post-surgery and 12 healthy controls performed a hop activity while lower limb muscle EMG was recorded bilaterally. Osteoarthritis was evaluated based on MRI. ACLR muscle activity patterns were bilaterally symmetrical and differed from those of healthy controls, suggesting the presence of a global adaptation strategy. Smaller ipsilateral thigh muscle girth was the strongest predictor of inferior MRI scores. The ability of our EMG analysis approach to detect meaningful neuromuscular differences that could ultimately be related to thigh muscle girth provides the foundation to further investigate a direct link between muscle activation patterns and PTOA risk.
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影响因子：
3.3
作者：
Herzog MM;Marshall SW;Lund JL;Pate V;Mack CD;Spang JT
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Spang JT
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