Further Studies on the Pathogenesis of the Postgastrectomy Syndrome
Further Studies on the Pathogenesis of the Postgastrectomy Syndrome
复制标题
胃切除术后综合征发病机制的进一步研究
DOI：
10.1097/00000658-195712000-00002
复制
发表时间：
1957
影响因子：
9
通讯作者：
M. D. DE. BAKEY
中科院分区：
文献类型：
--
作者：
G. H. Peddie;G. L. Jordan;M. D. DE. BAKEY
手术过程改变了食物从结石进入肠道的正常通道，可能会引起生理或解剖变化，引起手术前不存在的症状。1913年，Hertz注意到一些胃肠吻合术患者的餐后症状，但他的观察在当时并没有引起多大兴趣。1922年，Mix* 描述了胃肠吻合术后钡在小肠中的积聚，并创造了术语“倾倒”。正如他所描述的，“倾倒”指的是X线摄影观察，但这个表达性术语很快被纳入医学术语，目前它经常被用作所有胃切除术后症状的包容性术语。然而，最近的调查导致了几种不同的胃切除术后综合征的描述，因此有必要使用更具体的术语。有一种倾向是将术语“倾倒”限于发生在餐后即刻的综合征，其特征是恶心、上腹部饱胀和翻腾、虚弱、出汗、呕吐和心动过速。严重的病例会出现呕吐和腹泻。为了区别于餐后2 ~ 4小时发生的由反跳性低血糖引起的类似综合征，这种综合征也被称为”早期胃切除术后综合征“。"
SURcCAL PRocEDUREs which alter the nor-mal passage of food from the stonach into the intestines may produce physiologic or anatomic changes which cause symptoms not present prior to operation. In 1913, Hertz* noted postprandial symptoms in some patients treated by gastroenterostomy, but his observation stinulated little interest at that time. In 1922, Mix* described pooling of barium in the small boweł following gastroenterostomy and coined the term “dumping." As he described it," dumping" referred to a roentgenographic observation, but this expressive term was rapidly incorporated into medical terminology, and currently it is often used as an inclusive term for all postgastrectomy symptoms. However, recent investigations have led to the delineation of several different postgastrectomy syndromes, so that it is necessary to use more specific terminology. There has been a tendency to limit the term “dumping” to that syndrome which occurs in the immediate postprandial period and is characterized by nausea, fullness and churning in the epigastrium, weakness, sweating, pałlor and tachycardia. In severe cases, vomiting and diarrhea ensue. To dif-ferentiate it from a similar symptom com-plex which occurs two to four hours postprandially and is the result of a rebound hypoglycemia, this symptom complex has also been designated the" early postgastrectomy syndrome."